Essential Pharmaceuticals, LCC, is based in Newtown, PA and provides medical researchers and manufacturers new tools to bring performance, convenience, and control to enhance the advancement of basic research and drug discovery. Essential Pharmaceuticals—Supporting the preservation and growth of human systems. From the cell to the entire organ, we look to advance medical treatments and the research that creates new medical treatments.
Established in 2006, the Essential Pharmaceuticals story actually goes back to the year 2000 with the launch of Custodiol® HTK organ preservation solution. At that time, Allan Weber, had brought the product to Odyssey Pharmaceuticals as a product in the company’s new organ transplant line of business. The product rapidly grew into a significant yet highly specialized business with its own sales team and marketing network.
In 2005, Odyssey’s parent company was in the process of being acquired by the only company in the US with a competitive product to Custodiol. Allan Weber, then General Manager for Odyssey, saw the opportunity with the divestiture necessitated by government regulations, and created Essential Pharmaceuticals, bringing the entire sales division with him. Allan Weber is our CEO.
Essential continued to grow Custodiol, and even sought studies for new indications at the FDA, which are ongoing. Essential explored new medical treatments in the area of transplant surgery, looking to capitalize on our years of support and learning with the surgeons and medical personnel. Essential’s search into how better preserve organs led it to start looking at how to preserve the cells of the organs themselves. With the leadership of Essential’s new Chief Science Officer, this led to a new business – the “Ess” line of products.
Now, after three years of development, Essential Pharmaceuticals has three new products ready for the market:
- Cell-Ess®: A serum free, totally synthetic serum replacement used to grow cells
- Cryo-Ess®: An animal component and toxic DMSO-free cryopreservative to preserve cells indefinitely in a frozen state.
- Clin-Ess®: An animal component free medium that can preserve tissue samples for study and diagnostic testing at cold or frozen temperatures.
Cell-Ess® product offers researchers the advantage of superior performance compared to serum. As a replacement for FBS or any other type of serum, Cell-Ess is a 100% synthetic, reproducible medium with no lot-to-lot variation. Cell-Ess is free of all animal components.
Cryo-Ess® is a replacement in cryopreservation for toxic dimethyl sulfoxide (DSMO). Cryo-Ess protects the cells from ice crystals by preventing crystallization during the thawing process, and has demonstrated synthetic reproducibility with no lot-to-lot variability.
Tissue specimens preserved with Clin-Ess® have less DNA and RNA degradation and fewer artifacts than those preserved using conventional methods, allowing for more efficient and safer tissue preservation than traditional methods. Additionally, Clin-Ess allows for transport without paraformaldehyde and as such does not effect downstream testing such as DNA and RNA tests.