Rational optimization of a monoclonal antibody improves the aggregation propensity and enhances the CMC properties along the entire pharmaceutical process chain
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Rational optimization of a monoclonal antibody improves the aggregation propensity and enhances the CMC properties along the entire pharmaceutical process chain
The discovery of therapeutic monoclonal antibodies (mAbs) mainly focuses on the biological activity they support the selection of highly potent drug candidates. these candidates, however, may have the physical attributes or chemical that causes a chemical that is not profitable, manufacturing, and controls (CMC) properties, such as titer inferior products, conformation and colloidal instability or poor solubility, which can inhibit or even prevent the development and manufacturing , Therefore, there is an urgent need to consider developability mAb candidates for lead identification and optimization.
This work provides a comprehensive proof of concept studies to significantly improve the developability of mAb variants that are optimized with the help of advanced in silico tool relative to the co-parenting a difficult-to-develop. Interestingly, a single amino acid substitutions in the variable domain of the light chain resulted in a three fold increase in titer of products after stable expression in Chinese hamster ovary cells. Microscopic investigation revealed that the wild type mAb-producing cells show potential inclusion antibody, whereas the cells in silico-producing optimized variants showed phenotype rescued.
Notably, the drug substance of variants in silico optimized contained substantially reduced levels of aggregate and fragment after the purification process downstream. Finally, the study formulations biodegrade significantly enhanced colloidal stability in silico optimized variants while folding and potential stability is maintained. This study emphasizes that the implementation of the initial bioinformatics lead generation and optimization of biotherapeutics reduce failures for further development activities and to support the reduction schedule and project resources.
Rational optimization of a monoclonal antibody improves the aggregation propensity and enhances the CMC properties along the entire pharmaceutical process chain
The quality and cost assessment of recombinant antibody fragments produced from mammalian, yeast and prokaryotic host cells: A case study before the development of pharmaceuticals.
monoclonal antibody fragment (Fab) are a promising class of therapeutic agents. Beatles aglycosylated protein expression and so many platforms have been developed including prokaryotic, yeast and mammalian cells. However, these platforms are not equal in terms of development of cell lines and culture time, product quality and the possibility of production costs greatly affect the success of the development of pharmaceutical drug candidates. This study is a humanized Fab fragment ACT017 ratings generated from two organisms (Escherichia coli and Pichia pastoris) and a host mammalian cell (CHO).
Following low production scale and Protein L-affinity purification in a generic condition, physico-chemical and functional quality of the assessment carried out prior to the economic analysis of industrial scale production using special software (Biosolve, Biopharm Services, UK).
The results showed a high titer production when using E. coli but related to the high heterogeneity of the protein content in the supernatant recovered. We also observed from Fab glycoforms produced from P. pastoris, while Fab secreted from CHO is the most homogeneous culture despite a longer time and a slightly higher estimate of the cost of goods. This study may help inform future pharmaceutical development of this class of therapeutic proteins.
Advanced Glycosylation End Product Specific Receptor (AGER) Antibody
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Mouse Advanced Glycosylation End Product Specific Receptor (AGER) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Mouse Advanced Glycosylation End Product Specific Receptor (AGER)CLIA Kit
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Mouse Advanced Glycosylation End Product Specific Receptor (AGER) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Mouse Advanced Glycosylation End Product Specific Receptor (AGER)CLIA Kit
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Mouse Advanced Glycosylation End Product Specific Receptor (AGER) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Mouse Advanced Glycosylation End Product Specific Receptor (AGER)CLIA Kit
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Mouse Advanced Glycosylation End Product Specific Receptor (AGER) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Mouse Advanced Glycosylation End Product Specific Receptor (AGER) CLIA Kit
Description: Double-antibody Sandwich chemiluminescent immunoassay for detection of Mouse Advanced Glycosylation End Product Specific Receptor (AGER)Serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids
Rat Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Advanced Glycosylation End Product Specific Receptor (AGER) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Rat Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Advanced Glycosylation End Product Specific Receptor (AGER) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Rat Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Advanced Glycosylation End Product Specific Receptor (AGER) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Rat Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Rat Advanced Glycosylation End Product Specific Receptor (AGER) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Rat Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Rat Advanced Glycosylation End Product Specific Receptor (AGER) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.
Advanced Glycosylation End Product Specific Receptor (AGER) Polyclonal Antibody (Rat), APC
Description: A sandwich quantitative ELISA assay kit for detection of Human Advanced Glycosylation End Product Specific Receptor (AGER) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit
Description: A sandwich quantitative ELISA assay kit for detection of Human Advanced Glycosylation End Product Specific Receptor (AGER) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Mouse Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Advanced Glycosylation End Product Specific Receptor (AGER) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Mouse Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit
Description: A sandwich quantitative ELISA assay kit for detection of Mouse Advanced Glycosylation End Product Specific Receptor (AGER) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Mouse Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Advanced Glycosylation End Product Specific Receptor (AGER) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Advanced Glycosylation End Product Specific Receptor (AGER) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Advanced Glycosylation End Product Specific Receptor (AGER) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Advanced Glycosylation End Product Specific Receptor (AGER) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Advanced Glycosylation End Product Specific Receptor (AGER) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.
Mouse Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Advanced Glycosylation End Product Specific Receptor (AGER) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Mouse Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Advanced Glycosylation End Product Specific Receptor (AGER) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Mouse Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Advanced Glycosylation End Product Specific Receptor (AGER) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Mouse Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Mouse Advanced Glycosylation End Product Specific Receptor (AGER) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Mouse Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Mouse Advanced Glycosylation End Product Specific Receptor (AGER) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.
Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit
Description: A sandwich ELISA kit for detection of Advanced Glycosylation End Product Specific Receptor from Rat in samples from blood, serum, plasma, cell culture fluid and other biological fluids.
Advanced Glycosylation End Product Specific Receptor (AGER) Polyclonal Antibody (Mouse, Rat), PE
Description: A Rabbit polyclonal antibody against Mouse, Rat Advanced Glycosylation End Product Specific Receptor (AGER). This antibody is labeled with PE.
Human Advanced Glycosylation End Product Specific Receptor / RAGE (AGER) CLIA Kit
Description: A sandwich ELISA kit for detection of Advanced Glycosylation End Product Specific Receptor from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.
ELISA kit for Human AGER (Advanced Glycosylation End Product Specific Receptor)
Description: A sandwich ELISA kit for detection of Advanced Glycosylation End Product Specific Receptor from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.
Guinea pig Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit
Description: A Rabbit polyclonal antibody against Rat Advanced Glycosylation End Product Specific Receptor (AGER). This antibody is labeled with Biotin.
Advanced Glycosylation End Product Specific Receptor (AGER) Polyclonal Antibody (Human, Mouse), APC
Description: A Rabbit polyclonal antibody against Human, Mouse Advanced Glycosylation End Product Specific Receptor (AGER). This antibody is labeled with APC.
Advanced Glycosylation End Product Specific Receptor (AGER) Polyclonal Antibody (Human, Mouse), Cy3
Description: A Rabbit polyclonal antibody against Human, Mouse Advanced Glycosylation End Product Specific Receptor (AGER). This antibody is labeled with Cy3.
Advanced Glycosylation End Product Specific Receptor (AGER) Polyclonal Antibody (Human, Mouse), FITC
Description: A Rabbit polyclonal antibody against Human, Mouse Advanced Glycosylation End Product Specific Receptor (AGER). This antibody is labeled with FITC.
Advanced Glycosylation End Product Specific Receptor (AGER) Polyclonal Antibody (Human, Mouse), HRP
Description: A Rabbit polyclonal antibody against Human, Mouse Advanced Glycosylation End Product Specific Receptor (AGER). This antibody is labeled with HRP.
Advanced Glycosylation End Product Specific Receptor (AGER) Polyclonal Antibody (Human, Mouse), PE
Description: A Rabbit polyclonal antibody against Human, Mouse Advanced Glycosylation End Product Specific Receptor (AGER). This antibody is labeled with PE.
Advanced Glycosylation End Product Specific Receptor (AGER) Polyclonal Antibody (Mouse, Rat), APC
Description: A Rabbit polyclonal antibody against Mouse, Rat Advanced Glycosylation End Product Specific Receptor (AGER). This antibody is labeled with APC.
Advanced Glycosylation End Product Specific Receptor (AGER) Polyclonal Antibody (Mouse, Rat), Cy3
Description: A Rabbit polyclonal antibody against Mouse, Rat Advanced Glycosylation End Product Specific Receptor (AGER). This antibody is labeled with Cy3.
Advanced Glycosylation End Product Specific Receptor (AGER) Polyclonal Antibody (Mouse, Rat), FITC
Description: A Rabbit polyclonal antibody against Mouse, Rat Advanced Glycosylation End Product Specific Receptor (AGER). This antibody is labeled with FITC.
Advanced Glycosylation End Product Specific Receptor (AGER) Polyclonal Antibody (Mouse, Rat), HRP
Description: A Rabbit polyclonal antibody against Mouse, Rat Advanced Glycosylation End Product Specific Receptor (AGER). This antibody is labeled with HRP.
Advanced Glycosylation End Product Specific Receptor (AGER) Polyclonal Antibody (Rat), APC-Cy7
Description: A Rabbit polyclonal antibody against Rat Advanced Glycosylation End Product Specific Receptor (AGER). This antibody is labeled with APC-Cy7.
CLIA kit for Rat AGER (Total Advanced Glycosylation End Product Specific Receptor)
Description: A sandwich CLIA kit for quantitative measurement of Rat AGER (Total Advanced Glycosylation End Product Specific Receptor) in samples from Serum, Plasma, Cell supernatant
Advanced Glycosylation End Product Specific Receptor (AGER) Polyclonal Antibody (Mouse, Rat), APC-Cy7
Description: A Rabbit polyclonal antibody against Mouse, Rat Advanced Glycosylation End Product Specific Receptor (AGER). This antibody is labeled with APC-Cy7.
CLIA kit for Human AGER (Total Advanced Glycosylation End Product Specific Receptor)
Description: A sandwich CLIA kit for quantitative measurement of Human AGER (Total Advanced Glycosylation End Product Specific Receptor) in samples from Serum, Plasma, Cell supernatant
ELISA kit for Rat AGER (Total Advanced Glycosylation End Product Specific Receptor)
Description: A sandwich ELISA kit for quantitative measurement of Rat AGER (Total Advanced Glycosylation End Product Specific Receptor) in samples from Serum, Plasma, Cell supernatant
CLIA kit for Mouse AGER (Total Advanced Glycosylation End Product Specific Receptor)
Description: A sandwich CLIA kit for quantitative measurement of Mouse AGER (Total Advanced Glycosylation End Product Specific Receptor) in samples from Serum, Plasma, Cell supernatant
ELISA kit for Mouse AGER (Total Advanced Glycosylation End Product Specific Receptor)
Description: A sandwich ELISA kit for quantitative measurement of Mouse AGER (Total Advanced Glycosylation End Product Specific Receptor) in samples from Serum, Plasma, Cell supernatant
ELISA kit for Human AGER (Total Advanced Glycosylation End Product Specific Receptor)
Description: A sandwich ELISA kit for quantitative measurement of Human AGER (Total Advanced Glycosylation End Product Specific Receptor) in samples from Serum, Plasma, Cell supernatant
Advanced Glycosylation End Product-Specific Receptor (AGER) Antibody
Description: A Rabbit polyclonal antibody against Human, Mouse Advanced Glycosylation End Product Specific Receptor (AGER). This antibody is labeled with Biotin.
Advanced Glycosylation End Product Specific Receptor (AGER) Polyclonal Antibody (Mouse, Rat), Biotinylated
Description: A Rabbit polyclonal antibody against Mouse, Rat Advanced Glycosylation End Product Specific Receptor (AGER). This antibody is labeled with Biotin.
Advanced Glycosylation End Product Specific Receptor (AGER) Polyclonal Antibody (Human, Mouse), APC-Cy7
Description: A Rabbit polyclonal antibody against Human, Mouse Advanced Glycosylation End Product Specific Receptor (AGER). This antibody is labeled with APC-Cy7.
AGER ELISA Kit| Rat Advanced Glycosylation End Product Specific
Description: A competitive ELISA for quantitative measurement of Rat Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rat Advanced Glycosylation End Product Specific Receptor ELISA kit
Description: A competitive ELISA for quantitative measurement of Rat Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rat Advanced Glycosylation End Product Specific Receptor ELISA kit
Description: A competitive ELISA for quantitative measurement of Rat Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Goat Advanced Glycosylation End Product Specific Receptor ELISA kit
Description: A competitive ELISA for quantitative measurement of Goat Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Goat Advanced Glycosylation End Product Specific Receptor ELISA kit
Description: A competitive ELISA for quantitative measurement of Goat Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Goat Advanced Glycosylation End Product Specific Receptor ELISA kit
Description: A competitive ELISA for quantitative measurement of Goat Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Pig Advanced Glycosylation End Product Specific Receptor ELISA kit
Description: A competitive ELISA for quantitative measurement of Porcine Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Pig Advanced Glycosylation End Product Specific Receptor ELISA kit
Description: A competitive ELISA for quantitative measurement of Porcine Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Pig Advanced Glycosylation End Product Specific Receptor ELISA kit
Description: A competitive ELISA for quantitative measurement of Porcine Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Dog Advanced Glycosylation End Product Specific Receptor ELISA kit
Description: A competitive ELISA for quantitative measurement of Canine Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Dog Advanced Glycosylation End Product Specific Receptor ELISA kit
Description: A competitive ELISA for quantitative measurement of Canine Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Dog Advanced Glycosylation End Product Specific Receptor ELISA kit
Description: A competitive ELISA for quantitative measurement of Canine Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Monkey Advanced Glycosylation End Product Specific Receptor ELISA kit
Description: A competitive ELISA for quantitative measurement of Monkey Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Monkey Advanced Glycosylation End Product Specific Receptor ELISA kit
Description: A competitive ELISA for quantitative measurement of Monkey Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Monkey Advanced Glycosylation End Product Specific Receptor ELISA kit
Description: A competitive ELISA for quantitative measurement of Monkey Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Mouse Advanced Glycosylation End Product Specific Receptor ELISA kit
Description: A competitive ELISA for quantitative measurement of Mouse Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Mouse Advanced Glycosylation End Product Specific Receptor ELISA kit
Description: A competitive ELISA for quantitative measurement of Mouse Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Mouse Advanced Glycosylation End Product Specific Receptor ELISA kit
Description: A competitive ELISA for quantitative measurement of Mouse Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rabbit Advanced Glycosylation End Product Specific Receptor ELISA kit
Description: A competitive ELISA for quantitative measurement of Rabbit Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rabbit Advanced Glycosylation End Product Specific Receptor ELISA kit
Description: A competitive ELISA for quantitative measurement of Rabbit Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Rabbit Advanced Glycosylation End Product Specific Receptor ELISA kit
Description: A competitive ELISA for quantitative measurement of Rabbit Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Human Advanced Glycosylation End Product Specific Receptor ELISA kit
Description: A competitive ELISA for quantitative measurement of Human Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Human Advanced Glycosylation End Product Specific Receptor ELISA kit
Description: A competitive ELISA for quantitative measurement of Human Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Human Advanced Glycosylation End Product Specific Receptor ELISA kit
Description: A competitive ELISA for quantitative measurement of Human Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Human Advanced glycosylation end product-specific receptor (AGER)
Description: A competitive ELISA for quantitative measurement of Guinea pig Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Guinea pig Advanced Glycosylation End Product Specific Receptor ELISA kit
Description: A competitive ELISA for quantitative measurement of Guinea pig Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
Guinea pig Advanced Glycosylation End Product Specific Receptor ELISA kit
Description: A competitive ELISA for quantitative measurement of Guinea pig Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.
AGER ELISA Kit| Mouse Advanced Glycosylation End Product Specifi
Description: Quantitativesandwich ELISA kit for measuring Rat Advanced glycosylation end product-specific receptor (AGER) in samples from serum, plasma, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Rat Advanced glycosylation end product-specific receptor(AGER) ELISA kit
Description: Quantitativesandwich ELISA kit for measuring Rat Advanced glycosylation end product-specific receptor(AGER) in samples from serum, plasma, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
ELISA kit for Rat sAGER (Soluble Advanced Glycosylation End Product Specific Receptor)
Description: A sandwich ELISA kit for quantitative measurement of Rat sAGER (Soluble Advanced Glycosylation End Product Specific Receptor) in samples from Serum, Plasma, Cell supernatant
Human Advanced Glycosylation End Product-Specific Receptor (AGER) ELISA Kit
Description: Quantitativesandwich ELISA kit for measuring Mouse Advanced glycosylation end product-specific receptor (AGER) in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Mouse Advanced glycosylation end product-specific receptor(AGER) ELISA kit
Description: Quantitativesandwich ELISA kit for measuring Mouse Advanced glycosylation end product-specific receptor(AGER) in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
ELISA kit for Human sAGER (Soluble Advanced Glycosylation End Product Specific Receptor)
Description: A sandwich ELISA kit for quantitative measurement of Human sAGER (Soluble Advanced Glycosylation End Product Specific Receptor) in samples from Serum, Plasma, Cell supernatant
Mouse Ager/ Advanced glycosylation end product-specific receptor ELISA Kit
Description: Quantitative sandwich ELISA for measuring Rat Advanced glycosylation end product-specific receptor (AGER) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Rat Advanced glycosylation end product-specific receptor (AGER)
Description: Quantitative sandwich ELISA for measuring Rat Advanced glycosylation end product-specific receptor (AGER) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Rat Advanced glycosylation end product-specific receptor (AGER)
Description: Quantitative sandwich ELISA for measuring Rat Advanced glycosylation end product-specific receptor (AGER) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Mouse Advanced glycosylation end product-specific receptor (AGER)
Description: Quantitative sandwich ELISA for measuring Mouse Advanced glycosylation end product-specific receptor (AGER) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Mouse Advanced glycosylation end product-specific receptor (AGER)
Description: Quantitative sandwich ELISA for measuring Mouse Advanced glycosylation end product-specific receptor (AGER) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
ELISA kit for Mouse Advanced glycosylation end product-specific receptor (AGER)
Description: Quantitative sandwich ELISA for measuring Mouse Advanced glycosylation end product-specific receptor (AGER) in samples from cell culture supernatants, serum, whole blood, plasma and other biological fluids.
Mouse esRAGE(Endogenous secretory Advanced Glycosylation End Product Specific Receptor) ELISA Kit
Description: A sandwich ELISA kit for quantitative measurement of Rat esRAGE (Endogenous secretory Advanced Glycosylation End Product Specific Receptor) in samples from Serum, Plasma, Cell supernatant
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Names and indications of therapeutic monoclonal antibodies must comply with applicable regulations, which do not prevent the development of commercial strategies across the tradename. Some of these practices are based on legal considerations or the region while others are motivated by a real medical concerns. Finally, some have a significant financial impact on society.