Obatoclax |
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27044 |
BPS Bioscience |
5 mg |
EUR 120 |
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Description: Obatoclax, also known as GX15-070, is a novel Bcl-2 homology domain-3 (BH3) mimetic. It occupies a hydrophobic cleft within the BH3 binding groove of Bcl-2, antagonizing Bcl-2 and thus inducing apoptosis. Obatoclax inhibited primary acute myeloid leukemia (AML) progenitor cell proliferation with an average IC50 of 0.18 ± 0.07 µM, and it potently induced apoptosis in primary AML cells with an average IC50 of 3.6 ± 1.2 µM. Obatoclax overcomes Bcl-2-, Bcl-xL-, Bcl-w-, and Mcl-1-mediated resistance to BAX or BAK and to the proteasome inhibitor bortezomib. |
Human IgG antibody Laboratories manufactures the https://lclabs.com/search.html?addsearch=obatoclax &commit=go reagents distributed by Genprice. The Https://Lclabs.Com/Search.Html?Addsearch=Obatoclax &Commit=Go reagent is RUO (Research Use Only) to test human serum or cell culture lab samples. To purchase these products, for the MSDS, Data Sheet, protocol, storage conditions/temperature or for the concentration, please contact LC laboratories. Other Https://Lclabs.Com/Search.Html?Addsearch=Obatoclax products are available in stock. Specificity: Https://Lclabs.Com/Search.Html?Addsearch=Obatoclax Category: &Commit=Go
Obatoclax |
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MedChemExpress |
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Ask for price |
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Description: Obatoclax (GX15-070), a BH3 mimetic, is a pan-BCL-2 family proteins inhibitor with a Ki of 220 nM for BCL-2[1][2]. Obatoclax induces autophagy-dependent cell death and targets cyclin D1 for proteasomal degradation. Obatoclax has anti-cancer and broad-spectrum antiparasitic activity[3][4]. |
Chemicals information
Obatoclax Mesylate |
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MBS578837-50mg |
MyBiosource |
50mg |
EUR 275 |
Obatoclax Mesylate |
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MBS578837-5mg |
MyBiosource |
5mg |
EUR 150 |
Obatoclax (GX15-070) |
|
E1KS1057 |
EnoGene |
5 mg |
EUR 816 |
Obatoclax (GX15-070) |
|
abx282740-100g |
Abbexa |
100 µg |
Ask for price |
Obatoclax (GX15-070) |
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abx282740-20g |
Abbexa |
20 µg |
EUR 143.75 |
Obatoclax (GX15-070) |
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abx282740-50g |
Abbexa |
50 µg |
EUR 375 |
Obatoclax (GX15-070) |
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MBS8506319-5mg |
MyBiosource |
5mg |
EUR 900 |
Obatoclax (GX15-070) |
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MBS8506319-5x5mg |
MyBiosource |
5x5mg |
EUR 3900 |
Obatoclax mesylate (GX15-070) |
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A4194-10 |
ApexBio |
10 mg |
EUR 143 |
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Description: Potent Bcl-2 inhibitor |
Obatoclax mesylate (GX15-070) |
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A4194-100 |
ApexBio |
100 mg |
EUR 1534.8 |
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Description: Obatoclax mesylate, also known as GX15-070, is a hydrophobic small molecule that potently inhibits BCL-2 family by binding to the BH3-binding site of BCL-2 and other related BCL-2 family members (including BCL-XL, MCL-1, A1, and BCL-B). |
Obatoclax mesylate (GX15-070) |
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A4194-25 |
ApexBio |
25 mg |
EUR 236 |
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|
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Description: Potent Bcl-2 inhibitor |
Obatoclax mesylate (GX15-070) |
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A4194-5 |
ApexBio |
5 mg |
EUR 80 |
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|
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Description: Potent Bcl-2 inhibitor |
Obatoclax mesylate (GX15-070) |
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A4194-5.1 |
ApexBio |
10 mM (in 1mL DMSO) |
EUR 69 |
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Description: Potent Bcl-2 inhibitor |
Obatoclax mesylate (GX15-070) |
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A4194-50 |
ApexBio |
50 mg |
EUR 395 |
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Description: Potent Bcl-2 inhibitor |
Obatoclax mesylate (GX15-070) |
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A4194-S |
ApexBio |
Evaluation Sample |
EUR 22 |
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Description: Potent Bcl-2 inhibitor |
Obatoclax mesylate (GX15-070) |
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MBS132122-100mg |
MyBiosource |
100mg |
EUR 1065 |
