Keeping pace with the increasing demand for high quality drug candidates in pharmaceutical research: Development of a new two-step preparative tandem high performance chromatographic system for the purification of antibodies.

In the field of biological drug development, high throughput (HT) technology is the key to identifying the most promising therapeutic candidates in an efficient manner and time-competitive market. While efficient cloning and expression of the existing methods, HT downstream processing mainly relies on applying liquid handling workstation miniature chromatography column or resin-based 96-well plate to shorten the development time. However, there is still a shortage of generic, preparative chromatographic method without aggregates and endotoxin with sufficient throughput.

The only thing that really generic antibody purification strategies including the removal of efficient dimer consisting of Protein A capture followed by size exclusion chromatography (SEC) as a polishing step. Other polishing methods, including IEX, HIC, and CHT, requires fine tuning specific antibodies. However, the standard setup preparative SEC tends to be somewhat time consuming, and limits throughput. In this work, we designed a unique chromatography setup enables a two-step purification of IgG unattended on a milligram scale directly from the 35 mL cell supernatant clarified, processing up to 48 samples in 44.0 hours.

By introducing the silica-based SEC columns, a preparative SEC can be accelerated. By further developing the HT two-step preparative Protein A / alternating column regeneration SEC system using the Agilent 1260 Infinity LC components, mAbs may be purified generally by two chromatographic steps in 55 minutes. In this way, by using a valve 2-position / 10-port and two quaternary pump, two SEC column can be run in parallel, excluding cleaning and balancing the phase of the actual cycle time. With further implement the third pump, Protein step can be run independently, resulting in a time-optimized nesting process.

By introducing CETAC ASX-520 autosampler, 48 samples can be run automatically without user intervention more than two business days. Advanced highly reproducible system for all human IgG1 antibodies tested, easily produce scale milligrams enough material for a full characterization of the antibodies and for their use in in vitro and in vivo activity assessment.

 Keeping pace with the increasing demand for high quality drug candidates in pharmaceutical research: Development of a new two-step preparative tandem high performance chromatographic system for the purification of antibodies.
Keeping pace with the increasing demand for high quality drug candidates in pharmaceutical research: Development of a new two-step preparative tandem high performance chromatographic system for the purification of antibodies.

Pharmaceutical Characterization of tropomyosin receptor kinase B-agonistic human antibodies induced pluripotent stem (HIPS) Cell-Derived Neurons.

Brain-derived neurotrophic factor (BDNF) is a central modulator of neuronal development and synaptic plasticity in the central nervous system. This makes BDNF-modulated tropomyosin receptor kinase B (TrkB) promising drug targets for treating synaptic dysfunction. Using growth factor-driven expansion and inhibition of Notch (Grinch) during maturation, called the Grinch neurons derived from pluripotent stem cells caused by humans.

This Grinch neurons used as a cell model for pharmacological profiles of the two antibodies TrkB-athletic, hereinafter referred to as AB2 and AB20 in the next-generation sequencing studies, AB2 and AB20 stimulated transcription changes, which broadly overlap with BDNF-driven transcriptional modulation. In connection with TrkB phosphorylation, both AB2 and AB20 only about half as efficacious as BDNF;

Human Glycosylation Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

abx354394-1096tests 10 × 96 tests Ask for price

Human Glycosylation Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

abx354394-596tests 5 × 96 tests
EUR 525

Chicken Glycosylation Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

abx356555-96tests 96 tests
EUR 990

Human GlyCAM1(Glycosylation Dependent Cell Adhesion Molecule 1) ELISA Kit

RE2169H-48wells 48 wells
EUR 125.55

Human GlyCAM1(Glycosylation Dependent Cell Adhesion Molecule 1) ELISA Kit

RE2169H-96wells 96 wells
EUR 179.55

Human GlyCAM1 (Glycosylation Dependent Cell Adhesion Molecule 1) ELISA Kit

MBS2513181-10x96Tests 10x96Tests
EUR 4060

Human GlyCAM1 (Glycosylation Dependent Cell Adhesion Molecule 1) ELISA Kit

MBS2513181-24Tests 24Tests
EUR 265

Human GlyCAM1 (Glycosylation Dependent Cell Adhesion Molecule 1) ELISA Kit

MBS2513181-48Tests 48Tests
EUR 450

Human GlyCAM1 (Glycosylation Dependent Cell Adhesion Molecule 1) ELISA Kit

MBS2513181-5x96Tests 5x96Tests
EUR 2265

Human GlyCAM1 (Glycosylation Dependent Cell Adhesion Molecule 1) ELISA Kit

MBS2513181-96Tests 96Tests
EUR 535

Rabbit GlyCAM1 (Glycosylation Dependent Cell Adhesion Molecule 1) ELISA Kit

MBS2512252-10x96Tests 10x96Tests
EUR 4445

Rabbit GlyCAM1 (Glycosylation Dependent Cell Adhesion Molecule 1) ELISA Kit

MBS2512252-24Tests 24Tests
EUR 280

Rabbit GlyCAM1 (Glycosylation Dependent Cell Adhesion Molecule 1) ELISA Kit

MBS2512252-48Tests 48Tests
EUR 495

Rabbit GlyCAM1 (Glycosylation Dependent Cell Adhesion Molecule 1) ELISA Kit

MBS2512252-5x96Tests 5x96Tests
EUR 2480

Rabbit GlyCAM1 (Glycosylation Dependent Cell Adhesion Molecule 1) ELISA Kit

MBS2512252-96Tests 96Tests
EUR 585

Monkey GlyCAM1 (Glycosylation Dependent Cell Adhesion Molecule 1) ELISA Kit

MBS2509163-10x96Tests 10x96Tests
EUR 4445

Monkey GlyCAM1 (Glycosylation Dependent Cell Adhesion Molecule 1) ELISA Kit

MBS2509163-24Tests 24Tests
EUR 280

Monkey GlyCAM1 (Glycosylation Dependent Cell Adhesion Molecule 1) ELISA Kit

MBS2509163-48Tests 48Tests
EUR 495

Monkey GlyCAM1 (Glycosylation Dependent Cell Adhesion Molecule 1) ELISA Kit

MBS2509163-5x96Tests 5x96Tests
EUR 2480

Monkey GlyCAM1 (Glycosylation Dependent Cell Adhesion Molecule 1) ELISA Kit

MBS2509163-96Tests 96Tests
EUR 585

Human GlyCAM1(Glycosylation Dependent Cell Adhesion Molecule 1) ELISA Kit

RE2169H-48wellsplate 48 wells plate
EUR 126

Human GlyCAM1(Glycosylation Dependent Cell Adhesion Molecule 1) ELISA Kit

RE2169H-96wellsplate 96 wells plate
EUR 180

Chicken GlyCAM1 (Glycosylation Dependent Cell Adhesion Molecule 1) ELISA Kit

MBS2506357-10x96Tests 10x96Tests
EUR 4445

Chicken GlyCAM1 (Glycosylation Dependent Cell Adhesion Molecule 1) ELISA Kit

MBS2506357-24Tests 24Tests
EUR 280

Chicken GlyCAM1 (Glycosylation Dependent Cell Adhesion Molecule 1) ELISA Kit

MBS2506357-48Tests 48Tests
EUR 495

Chicken GlyCAM1 (Glycosylation Dependent Cell Adhesion Molecule 1) ELISA Kit

MBS2506357-5x96Tests 5x96Tests
EUR 2480

Chicken GlyCAM1 (Glycosylation Dependent Cell Adhesion Molecule 1) ELISA Kit

MBS2506357-96Tests 96Tests
EUR 585

Porcine GlyCAM1 (Glycosylation Dependent Cell Adhesion Molecule 1) ELISA Kit

MBS2500247-10x96Tests 10x96Tests
EUR 4445

Porcine GlyCAM1 (Glycosylation Dependent Cell Adhesion Molecule 1) ELISA Kit

MBS2500247-24Tests 24Tests
EUR 280

Porcine GlyCAM1 (Glycosylation Dependent Cell Adhesion Molecule 1) ELISA Kit

MBS2500247-48Tests 48Tests
EUR 495

Porcine GlyCAM1 (Glycosylation Dependent Cell Adhesion Molecule 1) ELISA Kit

MBS2500247-5x96Tests 5x96Tests
EUR 2480

Porcine GlyCAM1 (Glycosylation Dependent Cell Adhesion Molecule 1) ELISA Kit

MBS2500247-96Tests 96Tests
EUR 585

ELISA kit for Human GlyCAM1 (Glycosylation Dependent Cell Adhesion Molecule 1)

E-EL-H1996 1 plate of 96 wells
EUR 640.8
Description: A sandwich ELISA kit for quantitative measurement of Human GlyCAM1 (Glycosylation Dependent Cell Adhesion Molecule 1) in samples from Serum, Plasma, Cell supernatant

Glycam1 (untagged) - Mouse glycosylation dependent cell adhesion molecule 1 (Glycam1), (10ug)

MC208561 10 µg Ask for price

Glycam1 (Myc-DDK-tagged) - Mouse glycosylation dependent cell adhesion molecule 1 (Glycam1)

MR221954 10 µg Ask for price

Glycam1 (GFP-tagged) - Mouse glycosylation dependent cell adhesion molecule 1 (Glycam1), (10ug)

MG221954 10 µg Ask for price

Glycam1 (untagged ORF) - Rat glycosylation dependent cell adhesion molecule 1 (Glycam1), (10 ug)

RN202678 10 µg Ask for price

Glycam1 (untagged) - Mouse glycosylation dependent cell adhesion molecule 1 (Glycam1), transcript variant 1

MC225792 10 µg Ask for price

Glycam1 (Myc-DDK-tagged ORF) - Rat glycosylation dependent cell adhesion molecule 1 (Glycam1), (10 ug)

RR202678 10 µg Ask for price

Lenti ORF clone of Glycam1 (mGFP-tagged) - Mouse glycosylation dependent cell adhesion molecule 1 (Glycam1)

MR221954L4 10 µg Ask for price

Lenti ORF clone of Glycam1 (Myc-DDK-tagged) - Mouse glycosylation dependent cell adhesion molecule 1 (Glycam1)

MR221954L3 10 µg Ask for price

Glycam1 (myc-DDK-tagged) - Mouse glycosylation dependent cell adhesion molecule 1 (Glycam1), transcript variant 1

MR228003 10 µg Ask for price

Lenti ORF clone of Glycam1 (mGFP-tagged ORF) - Rat glycosylation dependent cell adhesion molecule 1 (Glycam1), (10 ug)

RR202678L4 10 µg Ask for price

Goat Glycosylation-dependent cell adhesion molecule 1 (GLYCAM1) ELISA Kit

MBS283835-10x96StripWells 10x96-Strip-Wells
EUR 6840

Goat Glycosylation-dependent cell adhesion molecule 1 (GLYCAM1) ELISA Kit

MBS283835-48StripWells 48-Strip-Wells
EUR 480

Goat Glycosylation-dependent cell adhesion molecule 1 (GLYCAM1) ELISA Kit

MBS283835-5x96StripWells 5x96-Strip-Wells
EUR 3610

Goat Glycosylation-dependent cell adhesion molecule 1 (GLYCAM1) ELISA Kit

MBS283835-96StripWells 96-Strip-Wells
EUR 805

Goat Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918521-INQUIRE INQUIRE Ask for price

Lenti ORF clone of Glycam1 (Myc-DDK-tagged ORF) - Rat glycosylation dependent cell adhesion molecule 1 (Glycam1), (10 ug)

RR202678L3 10 µg Ask for price

Lenti ORF particles, Glycam1 (GFP-tagged) - Mouse glycosylation dependent cell adhesion molecule 1 (Glycam1), 200ul, >10^7 TU/mL

MR221954L4V 200 µl Ask for price

Lenti ORF particles, Glycam1 (GFP-tagged ORF) - Rat glycosylation dependent cell adhesion molecule 1 (Glycam1), 200ul, >10^7 TU/mL

RR202678L4V 200 µl Ask for price

Goat GLYCAM1 / Glycosylation-dependent cell adhesion molecule 1 ELISA Kit

E1565g 96T
EUR 900

Goat GLYCAM1/Glycosylation-Dependent Cell Adhesion Molecule 1 ELISA Kit

MBS2890782-10x96StripWells 10x96-Strip-Wells
EUR 4630

Goat GLYCAM1/Glycosylation-Dependent Cell Adhesion Molecule 1 ELISA Kit

MBS2890782-48StripWells 48-Strip-Wells
EUR 440

Goat GLYCAM1/Glycosylation-Dependent Cell Adhesion Molecule 1 ELISA Kit

MBS2890782-5x96StripWells 5x96-Strip-Wells
EUR 2480

Goat GLYCAM1/Glycosylation-Dependent Cell Adhesion Molecule 1 ELISA Kit

MBS2890782-96StripWells 96-Strip-Wells
EUR 580

Lenti ORF particles, Glycam1 (Myc-DDK-tagged ORF) - Rat glycosylation dependent cell adhesion molecule 1 (Glycam1), 200ul, >10^7 TU/mL

RR202678L3V 200 µl Ask for price

Lenti ORF particles, Glycam1 (Myc-DDK-tagged) - Mouse glycosylation dependent cell adhesion molecule 1 (Glycam1), 200ul, >10^7 TU/mL

MR221954L3V 200 µl Ask for price

Recombinant Goat Glycosylation-dependent cell adhesion molecule 1 (GLYCAM1)

MBS718434-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1060

Recombinant Goat Glycosylation-dependent cell adhesion molecule 1 (GLYCAM1)

MBS718434-002mgEColi 0.02mg(E-Coli)
EUR 640

Recombinant Goat Glycosylation-dependent cell adhesion molecule 1 (GLYCAM1)

MBS718434-002mgYeast 0.02mg(Yeast)
EUR 810

Recombinant Goat Glycosylation-dependent cell adhesion molecule 1 (GLYCAM1)

MBS718434-01mgEColi 0.1mg(E-Coli)
EUR 745

Recombinant Goat Glycosylation-dependent cell adhesion molecule 1 (GLYCAM1)

MBS718434-01mgYeast 0.1mg(Yeast)
EUR 950

Rat Glycosylation-dependent cell adhesion molecule 1 (GLYCAM1) ELISA Kit

RK08359 96T
EUR 280

Cat Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918515-INQUIRE INQUIRE Ask for price

Cavy Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918516-INQUIRE INQUIRE Ask for price

Duck Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918518-INQUIRE INQUIRE Ask for price

Fish Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918519-INQUIRE INQUIRE Ask for price

Rat Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918530-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918530-48StripWells 48-Strip-Wells
EUR 550

Rat Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918530-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918530-96StripWells 96-Strip-Wells
EUR 765

Bovine Glycosylation-dependent cell adhesion molecule 1 (GLYCAM1) ELISA Kit

RK08356 96T
EUR 280

Mouse Glycosylation-dependent cell adhesion molecule 1 (GLYCAM1) ELISA Kit

RK08358 96T
EUR 280

Bovine Glycosylation-dependent cell adhesion molecule 1, GLYCAM1 ELISA Kit

MBS9316670-10x96StripWells 10x96-Strip-Wells
EUR 6725

Bovine Glycosylation-dependent cell adhesion molecule 1, GLYCAM1 ELISA Kit

MBS9316670-48StripWells 48-Strip-Wells
EUR 550

Bovine Glycosylation-dependent cell adhesion molecule 1, GLYCAM1 ELISA Kit

MBS9316670-5x96StripWells 5x96-Strip-Wells
EUR 3420

Bovine Glycosylation-dependent cell adhesion molecule 1, GLYCAM1 ELISA Kit

MBS9316670-96StripWells 96-Strip-Wells
EUR 765

Canine Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918512-10x96StripWells 10x96-Strip-Wells
EUR 6725

Canine Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918512-48StripWells 48-Strip-Wells
EUR 550

Canine Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918512-5x96StripWells 5x96-Strip-Wells
EUR 3420

Canine Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918512-96StripWells 96-Strip-Wells
EUR 765

Camel Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918514-10x96StripWells 10x96-Strip-Wells
EUR 6725

Camel Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918514-48StripWells 48-Strip-Wells
EUR 550

Camel Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918514-5x96StripWells 5x96-Strip-Wells
EUR 3420

Camel Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918514-96StripWells 96-Strip-Wells
EUR 765

Donkey Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918517-INQUIRE INQUIRE Ask for price

Goose Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918520-INQUIRE INQUIRE Ask for price

Horse Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918522-10x96StripWells 10x96-Strip-Wells
EUR 6725

Horse Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918522-48StripWells 48-Strip-Wells
EUR 550

Horse Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918522-5x96StripWells 5x96-Strip-Wells
EUR 3420

Horse Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918522-96StripWells 96-Strip-Wells
EUR 765

Human Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918524-10x96StripWells 10x96-Strip-Wells
EUR 6725

Human Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918524-48StripWells 48-Strip-Wells
EUR 550

Human Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918524-5x96StripWells 5x96-Strip-Wells
EUR 3420

Human Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918524-96StripWells 96-Strip-Wells
EUR 765

Monkey Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918525-10x96StripWells 10x96-Strip-Wells
EUR 6725

Monkey Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918525-48StripWells 48-Strip-Wells
EUR 550

Monkey Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918525-5x96StripWells 5x96-Strip-Wells
EUR 3420

Monkey Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918525-96StripWells 96-Strip-Wells
EUR 765

Mouse Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918526-10x96StripWells 10x96-Strip-Wells
EUR 6725

Mouse Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918526-48StripWells 48-Strip-Wells
EUR 550

Mouse Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918526-5x96StripWells 5x96-Strip-Wells
EUR 3420

Mouse Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918526-96StripWells 96-Strip-Wells
EUR 765

Pigeon Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918527-INQUIRE INQUIRE Ask for price

Rabbit Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918529-INQUIRE INQUIRE Ask for price

Sheep Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918531-10x96StripWells 10x96-Strip-Wells
EUR 6725

Sheep Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918531-48StripWells 48-Strip-Wells
EUR 550

Sheep Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918531-5x96StripWells 5x96-Strip-Wells
EUR 3420

Sheep Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918531-96StripWells 96-Strip-Wells
EUR 765

Chicken Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918513-INQUIRE INQUIRE Ask for price

Hamster Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918523-10x96StripWells 10x96-Strip-Wells
EUR 6725

Hamster Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918523-48StripWells 48-Strip-Wells
EUR 550

Hamster Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918523-5x96StripWells 5x96-Strip-Wells
EUR 3420

Hamster Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918523-96StripWells 96-Strip-Wells
EUR 765

Porcine Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918528-10x96StripWells 10x96-Strip-Wells
EUR 6725

Porcine Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918528-48StripWells 48-Strip-Wells
EUR 550

Porcine Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918528-5x96StripWells 5x96-Strip-Wells
EUR 3420

Porcine Glycosylation-Dependent Cell Adhesion Molecule 1 (GLYCAM1) ELISA Kit

MBS9918528-96StripWells 96-Strip-Wells
EUR 765

Goat Glycosylation-dependent cell adhesion molecule-1(GlyCAM-1) ELISA Kit

NSL0689Gt 96T
EUR 528

Goat glycosylation-dependent cell adhesion molecule-1 (GlyCAM-1) ELISA Kit

MBS263831-10x96StripWells 10x96-Strip-Wells
EUR 3545

Goat glycosylation-dependent cell adhesion molecule-1 (GlyCAM-1) ELISA Kit

MBS263831-48StripWells 48-Strip-Wells
EUR 310

Goat glycosylation-dependent cell adhesion molecule-1 (GlyCAM-1) ELISA Kit

MBS263831-5x96StripWells 5x96-Strip-Wells
EUR 1940

Goat glycosylation-dependent cell adhesion molecule-1 (GlyCAM-1) ELISA Kit

MBS263831-96StripWells 96-Strip-Wells
EUR 475

Goat glycosylation-dependent cell adhesion molecule-1(GlyCAM-1) ELISA Kit

EIA05732Go each
EUR 520

Rat Glycam1/ Glycosylation-dependent cell adhesion molecule 1 ELISA Kit

E0404Ra 1 Kit
EUR 557
Description: Endothelial ligand FOR L-selectin,SGP50,Sulfated 50 kDa glycoprotein

Rat Glycam1 / Glycosylation-dependent cell adhesion molecule 1 ELISA Kit

E1565r 96T
EUR 796

Mouse Glycam1/ Glycosylation-dependent cell adhesion molecule 1 ELISA Kit

E0605Mo 1 Kit
EUR 543
Description: Endothelial ligand FOR L-selectin,MC26,SGP50,Sulfated 50 kDa glycoprotein

Bovine GLYCAM1/ Glycosylation-dependent cell adhesion molecule 1 ELISA Kit

E0115Bo 1 Kit
EUR 630
Description: 28 kDa milk glycoprotein PP3,Lactophorin,Proteose-peptone component 3,PP3

Bovine GLYCAM1 / Glycosylation-dependent cell adhesion molecule 1 ELISA Kit

E1565b 96T
EUR 900

Mouse Glycam1 / Glycosylation-dependent cell adhesion molecule 1 ELISA Kit

E1565m 96T
EUR 776

Human Putative glycosylation-dependent cell adhesion molecule 1 (GLYCAM1) ELISA Kit

RK08357 96T
EUR 280

Human GLYCAM1/ Putative glycosylation-dependent cell adhesion molecule 1 ELISA Kit

E1026Hu 1 Kit
EUR 515

Human GLYCAM1 / Putative glycosylation-dependent cell adhesion molecule 1 ELISA Kit

E1565h 96T
EUR 736

Recombinant Rat Glycosylation-dependent cell adhesion molecule 1 (Glycam1)

MBS718691-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1050

Recombinant Rat Glycosylation-dependent cell adhesion molecule 1 (Glycam1)

MBS718691-002mgEColi 0.02mg(E-Coli)
EUR 630

Recombinant Rat Glycosylation-dependent cell adhesion molecule 1 (Glycam1)

MBS718691-002mgYeast 0.02mg(Yeast)
EUR 800

Recombinant Rat Glycosylation-dependent cell adhesion molecule 1 (Glycam1)

MBS718691-01mgEColi 0.1mg(E-Coli)
EUR 730

Recombinant Rat Glycosylation-dependent cell adhesion molecule 1 (Glycam1)

MBS718691-01mgYeast 0.1mg(Yeast)
EUR 940

Recombinant Bovine Glycosylation-dependent cell adhesion molecule 1 (GLYCAM1)

MBS964028-002mgBaculovirus 0.02mg(Baculovirus)
EUR 1055

Recombinant Bovine Glycosylation-dependent cell adhesion molecule 1 (GLYCAM1)

MBS964028-002mgEColi 0.02mg(E-Coli)
EUR 640

Recombinant Bovine Glycosylation-dependent cell adhesion molecule 1 (GLYCAM1)

MBS964028-002mgYeast 0.02mg(Yeast)
EUR 810

Recombinant Bovine Glycosylation-dependent cell adhesion molecule 1 (GLYCAM1)

MBS964028-01mgEColi 0.1mg(E-Coli)
EUR 745

Recombinant Bovine Glycosylation-dependent cell adhesion molecule 1 (GLYCAM1)

MBS964028-01mgYeast 0.1mg(Yeast)
EUR 950

Recombinant Lama glama Glycosylation-dependent cell adhesion molecule 1 (GLYCAM1)

MBS1261431-002mgBaculovirus 0.02mg(Baculovirus)
EUR 940

Recombinant Lama glama Glycosylation-dependent cell adhesion molecule 1 (GLYCAM1)

MBS1261431-002mgEColi 0.02mg(E-Coli)
EUR 490

Recombinant Lama glama Glycosylation-dependent cell adhesion molecule 1 (GLYCAM1)

MBS1261431-002mgYeast 0.02mg(Yeast)
EUR 690

Recombinant Lama glama Glycosylation-dependent cell adhesion molecule 1 (GLYCAM1)

MBS1261431-01mgEColi 0.1mg(E-Coli)
EUR 580

Recombinant Lama glama Glycosylation-dependent cell adhesion molecule 1 (GLYCAM1)

MBS1261431-01mgYeast 0.1mg(Yeast)
EUR 810

Rat Glycosylation-dependent cell adhesion molecule-1(GlyCAM-1) ELISA Kit

NSL0498r 96 Tests
EUR 498

Rat glycosylation-dependent cell adhesion molecule-1 (GlyCAM-1) ELISA Kit

MBS269011-10x96StripWells 10x96-Strip-Wells
EUR 3290

Rat glycosylation-dependent cell adhesion molecule-1 (GlyCAM-1) ELISA Kit

MBS269011-48StripWells 48-Strip-Wells
EUR 295

Rat glycosylation-dependent cell adhesion molecule-1 (GlyCAM-1) ELISA Kit

MBS269011-5x96StripWells 5x96-Strip-Wells
EUR 1800

Rat glycosylation-dependent cell adhesion molecule-1 (GlyCAM-1) ELISA Kit

MBS269011-96StripWells 96-Strip-Wells
EUR 450

Rat glycosylation-dependent cell adhesion molecule-1(GlyCAM-1) ELISA Kit

EIA05732r each
EUR 480

Human glycosylation-dependent cell adhesion molecule-1,GlyCAM-1 ELISA Kit

CN-04444H1 96T
EUR 590.4

Human glycosylation-dependent cell adhesion molecule-1,GlyCAM-1 ELISA Kit

CN-04444H2 48T
EUR 409.2

Human glycosylation-dependent cell adhesion molecule-1,GlyCAM-1 ELISA Kit

YLA2152HU-48T 48T Ask for price

Human glycosylation-dependent cell adhesion molecule-1,GlyCAM-1 ELISA Kit

YLA2152HU-96T 96T Ask for price

Human glycosylation-dependent cell adhesion molecule-1(GlyCAM-1)ELISA Kit

GA-E0309HM-48Tests 48 Tests Ask for price

Human glycosylation-dependent cell adhesion molecule-1(GlyCAM-1)ELISA Kit

GA-E0309HM-96Tests 96 Tests
EUR 388

Human glycosylation-dependent cell adhesion molecule-1(GlyCAM-1)ELISA Kit

GA-E0309HM-48T 48T
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Human glycosylation-dependent cell adhesion molecule-1(GlyCAM-1)ELISA Kit

GA-E0309HM-96T 96T
EUR 559.2

Human Glycosylation-dependent cell adhesion molecule-1(GlyCAM-1) ELISA Kit

NSL0569Hu 96 wells
EUR 468

Human glycosylation-dependent cell adhesion molecule-1(GlyCAM-1)ELISA Kit

QY-E01275 96T
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Human glycosylation-dependent cell adhesion molecule-1,GlyCAM-1 ELISA Kit

SL0793Hu 96 Tests
EUR 468

Human glycosylation-dependent cell adhesion molecule-1,GlyCAM-1 ELISA KIT

E0292Hu-1096T 10*96T
EUR 4122

Human glycosylation-dependent cell adhesion molecule-1,GlyCAM-1 ELISA KIT

E0292Hu-48wells 48 wells
EUR 300

Human glycosylation-dependent cell adhesion molecule-1,GlyCAM-1 ELISA KIT

E0292Hu-596T 5*96T
EUR 2061

However, with respect to TrkB signaling downstream, AB2 and AB20 displayed increased efficacy values, stimulating at least comparable with respect to the VGF BDNF transcription, as well as of AKT and cAMP response element-binding protein phosphorylation.In complex structure of domains TrkB-d5 with AB20 , determined by X-ray crystallography, AB20 discovered allosteric binding sites with respect to the binding sites BDNF, whereas AB2 is known to act orthosterically with BDNF. In agreement with these findings, AB2 and AB20 act synergistically at concentrations greater push TrkB phosphorylation.