Feasibility of antibody-poly(glutamic acid) complexes: preparation of high-concentration antibody formulations and their pharmaceutical properties.

High concentration antibody formulation development for subcutaneous administration the remains challenging. More recently, a precipitation-redissolution method is proposed to prepare a suspension or deposition of salt-morbidly protein-poly (amino acid) complex. To explain the usefulness of this method for therapeutic proteins, we investigated the feasibility of the method of precipitation-redissolution using poly (amino acids) for the formulation of high concentration antibody. Omalizumab and adalimumab formulation of 150 mg / mL can be prepared using acid poly-l-glutamate (polye) of low concentration stock solution.

Enzyme-linked immunosorbent assay, circular dichroism, and size-exclusion chromatography revealed that the formation of antibody-polye complex process and precipitation-redissolution does not significantly affect the immunoreactivity or secondary structure of the antibody. Redissolution-precipitation method is less time consuming and more effective than the lyophilization-redissolution, evaporation-redissolution, and ultrafiltration from the standpoint of the final outcome. Scalability is confirmed from 400 uL to 1.0 L. general toxicity and pharmacokinetic profile of the antibody-polye complex formulation that is similar to conventional antibody formulation.

These results indicate that the precipitation-redissolution method using poly (amino acids) has great potential as a method for the concentration of antibody formulation and use of drugs.
Oxidation of methionine residues is one of the damaged well known in the monoclonal antibody (mAb) therapy. Because oxidation of methionine can affect the efficacy and pharmacokinetic profiles of their level of oxidation should be strictly controlled during the period of their storage.

In this study, we observed that when antibody therapy is filled into syringes cyclo olefin-based polymers and stored in blister packs with oxygen absorbent, the production of methionine oxidation under thermal stress or light suppressed because of a decrease in dissolved oxygen concentration. Also unexpected, smaller amounts of high molecular weight species and acidic variants of antibodies produced under thermal or light pressure.

 Feasibility of antibody-poly(glutamic acid) complexes: preparation of high-concentration antibody formulations and their pharmaceutical properties.
Feasibility of antibody-poly(glutamic acid) complexes: preparation of high-concentration antibody formulations and their pharmaceutical properties.

Is the in vitro whole blood cytokine assays useful for detecting potential risks of severe infusion reactions monoclonal antibody drugs?

After a life threatening cytokine release syndrome (CRS) occurred in clinical studies of anti-CD28 monoclonal antibody (mAb) TGN1412, in vitro cytokine release test using human blood cells have been proposed for the non-clinical evaluation of the potential risk of CRS. Two basic assay format that is often used: human peripheral blood mononuclear cells (PBMC) with mAbs move, and whole blood with watery mAbs.

However, the suitability of whole blood cytokine assay (WBCA) has been questioned, because the sample size is not realistic to be needed to detect potential risks caused by TGN1412 CRS, which has a low sensitivity. We do WBCA using peripheral blood obtained from 68 healthy volunteers to compare the two mAbs high risk, analog TGN1412 superagonistic anti-CD28 mAb (CD28SA) and alemutuzumab FcγR-mediated, with low risk mAb, panitumumab.

Recombinant Advanced Glycosylation End Product Specific Receptor (AGER)

MBS2018483-02mg 0.2mg
EUR 615

Recombinant Advanced Glycosylation End Product Specific Receptor (AGER)

MBS2018483-05mg 0.5mg
EUR 1170

Recombinant Advanced Glycosylation End Product Specific Receptor (AGER)

MBS2029915-001mg 0.01mg
EUR 175

Recombinant Advanced Glycosylation End Product Specific Receptor (AGER)

MBS2029915-005mg 0.05mg
EUR 320

Recombinant Advanced Glycosylation End Product Specific Receptor (AGER)

MBS2029915-01mg 0.1mg
EUR 490

Recombinant Advanced Glycosylation End Product Specific Receptor (AGER)

MBS2029915-02mg 0.2mg
EUR 595

Recombinant Advanced Glycosylation End Product Specific Receptor (AGER)

MBS2029915-05mg 0.5mg
EUR 1130

Recombinant Advanced Glycosylation End Product Specific Receptor (AGER)

MBS2009621-001mg 0.01mg
EUR 170

Recombinant Advanced Glycosylation End Product Specific Receptor (AGER)

MBS2009621-005mg 0.05mg
EUR 295

Recombinant Advanced Glycosylation End Product Specific Receptor (AGER)

MBS2009621-01mg 0.1mg
EUR 445

Recombinant Advanced Glycosylation End Product Specific Receptor (AGER)

MBS2009621-02mg 0.2mg
EUR 540

Recombinant Advanced Glycosylation End Product Specific Receptor (AGER)

MBS2009621-05mg 0.5mg
EUR 1025

Human Advanced Glycosylation End Product Specific Receptor ELISA kit

E01A0477-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Advanced Glycosylation End Product Specific Receptor ELISA kit

E01A0477-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Advanced Glycosylation End Product Specific Receptor ELISA kit

E01A0477-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS015326-10x96StripWells 10x96-Strip-Wells
EUR 6725

Human Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS015326-48StripWells 48-Strip-Wells
EUR 550

Human Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS015326-5x96StripWells 5x96-Strip-Wells
EUR 3420

Human Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS015326-96StripWells 96-Strip-Wells
EUR 765

Human Advanced Glycosylation End Product Specific Receptor (AGER) Protein

20-abx065184
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Human Advanced Glycosylation End Product Specific Receptor (AGER) Protein

abx065184-100g 100 µg
EUR 425

Human Advanced Glycosylation End Product Specific Receptor (AGER) Protein

abx065184-200g 200 µg
EUR 625

Human Advanced Glycosylation End Product Specific Receptor (AGER) Protein

abx065184-50g 50 µg
EUR 237.5

Human Advanced Glycosylation End Product Specific Receptor (AGER) CLIA Kit

abx196212-96tests 96 tests
EUR 990

Human Advanced Glycosylation End Product Specific Receptor (AGER) CLIA Kit

abx196212-100l 100 µl
EUR 618.75

Human Advanced Glycosylation End Product Specific Receptor (AGER) CLIA Kit

abx196212-200l 200 µl Ask for price

Human AGER (Advanced Glycosylation End Product Specific Receptor) CLIA Kit

MBS2532217-5x96Tests 5x96Tests
EUR 2565

Human AGER (Advanced Glycosylation End Product Specific Receptor) CLIA Kit

MBS2532217-96Tests 96Tests
EUR 560

Human Receptor for advanced glycatiom end products/Advanced Glycosylation End Product Specific Receptor ELISA kit

E01A7517 96T
EUR 700
Description: ELISA

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

20-abx150586
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

abx252019-96tests 96 tests
EUR 848.4

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

abx253583-96tests 96 tests
EUR 848.4

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

DLR-AGER-Hu 96T
EUR 422
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

DLR-AGER-Hu-48T 48T
EUR 574.8
Description: A sandwich quantitative ELISA assay kit for detection of Human Advanced Glycosylation End Product Specific Receptor (AGER) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

DLR-AGER-Hu-96T 96T
EUR 745.2
Description: A sandwich quantitative ELISA assay kit for detection of Human Advanced Glycosylation End Product Specific Receptor (AGER) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

DL-AGER-Hu 96T
EUR 402
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

EK12506 96Т
EUR 768

Human Advanced Glycosylation End Product Specific Receptor ELISA Kit (AGER)

RK00844 96 Tests
EUR 280

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

RD-AGER-Hu-48T 48T
EUR 411.8
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

RD-AGER-Hu-48Tests 48 Tests
EUR 573.6

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

RD-AGER-Hu-96T 96T
EUR 588.3
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

RD-AGER-Hu-96Tests 96 Tests
EUR 794.4

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

RDR-AGER-Hu-48T 48T
EUR 432.39
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

RDR-AGER-Hu-48Tests 48 Tests
EUR 600

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

RDR-AGER-Hu-96T 96T
EUR 617.72
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

RDR-AGER-Hu-96Tests 96 Tests
EUR 830.4

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

SEA645Hu-10x96wellstestplate 10x96-wells test plate
EUR 5128.02
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Advanced Glycosylation End Product Specific Receptor (AGER) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

SEA645Hu-1x48wellstestplate 1x48-wells test plate
EUR 527.48
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Advanced Glycosylation End Product Specific Receptor (AGER) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

SEA645Hu-1x96wellstestplate 1x96-wells test plate
EUR 702.12
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Advanced Glycosylation End Product Specific Receptor (AGER) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

SEA645Hu-5x96wellstestplate 5x96-wells test plate
EUR 2799.54
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Advanced Glycosylation End Product Specific Receptor (AGER) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

4-SEA645Hu
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  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Advanced Glycosylation End Product Specific Receptor (AGER) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

MBS2023573-10x96StripWells 10x96-Strip-Wells
EUR 4910

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

MBS2023573-24StripWells 24-Strip-Wells
EUR 340

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

MBS2023573-48StripWells 48-Strip-Wells
EUR 500

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

MBS2023573-5x96StripWells 5x96-Strip-Wells
EUR 2675

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

MBS2023573-96StripWells 96-Strip-Wells
EUR 665

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

MBS457473-10x96Tests 10x96Tests
EUR 4890

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

MBS457473-48Tests 48Tests
EUR 425

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

MBS457473-5x96Tests 5x96Tests
EUR 2495

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

MBS457473-96Tests 96Tests
EUR 560

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

MBS455477-10x96StripWells 10x96-Strip-Wells
EUR 4700

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

MBS455477-48StripWells 48-Strip-Wells
EUR 410

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

MBS455477-5x96StripWells 5x96-Strip-Wells
EUR 2410

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

MBS455477-96StripWells 96-Strip-Wells
EUR 545

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

MBS2702210-10x96StripWells 10x96-Strip-Wells
EUR 2830

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

MBS2702210-24StripWells 24-Strip-Wells
EUR 240

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

MBS2702210-48StripWells 48-Strip-Wells
EUR 315

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

MBS2702210-5x96StripWells 5x96-Strip-Wells
EUR 1480

Human Advanced Glycosylation End Product Specific Receptor (AGER) ELISA Kit

MBS2702210-96StripWells 96-Strip-Wells
EUR 385

Advanced Glycosylation End Product Specific Receptor (AGER) Antibody

20-abx104577
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Advanced Glycosylation End Product Specific Receptor (AGER) Antibody

20-abx104578
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  • 100 ug
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  • 1 mg
  • 200 ug
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Advanced Glycosylation End Product Specific Receptor (AGER) Antibody

20-abx130064
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  • 100 ug
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  • 1 mg
  • 200 ug
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Advanced Glycosylation End Product Specific Receptor (AGER) Antibody

abx032323-400ul 400 ul
EUR 627.6

Advanced Glycosylation End Product Specific Receptor (AGER) Antibody

abx032323-80l 80 µl
EUR 343.2

Advanced Glycosylation End Product Specific Receptor (AGER) Antibody

abx036573-100ug 100 ug
EUR 469.2

Advanced Glycosylation End Product Specific Receptor (AGER) Antibody

20-abx001218
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  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Advanced Glycosylation End Product Specific Receptor (AGER) Antibody

20-abx211205
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  • 100 ul
  • 50 ul

Advanced Glycosylation End Product Specific Receptor (AGER) Antibody

20-abx211206
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  • 100 ul
  • 50 ul

Advanced Glycosylation End Product Specific Receptor (AGER) Antibody

abx230209-100ug 100 ug
EUR 577.2

Advanced Glycosylation End Product Specific Receptor (AGER) Antibody

20-abx175289
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  • 1 mg
  • 200 ug

Advanced Glycosylation End Product Specific Receptor (AGER) Antibody

20-abx171123
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  • 1 mg
  • 200 ug

Advanced Glycosylation End Product Specific Receptor (AGER) Antibody

20-abx324550
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  • 100 ug
  • 50 ug

Advanced Glycosylation End Product Specific Receptor (AGER) Antibody

abx130064-100l 100 µl
EUR 262.5

Advanced Glycosylation End Product Specific Receptor (AGER) Antibody

abx130064-1ml 1 ml
EUR 725

Advanced Glycosylation End Product Specific Receptor (AGER) Antibody

abx130064-200l 200 µl
EUR 337.5

Advanced Glycosylation End Product Specific Receptor (AGER) Antibody

abx171123-1ml 1 ml
EUR 712.5

Advanced Glycosylation End Product Specific Receptor (AGER) Antibody

abx036573-100g 100 µg
EUR 337.5

Advanced Glycosylation End Product Specific Receptor (AGER) Antibody

abx230209-100g 100 µg
EUR 350

Advanced Glycosylation End Product Specific Receptor (AGER) Antibody

abx104577-100g 100 µg
EUR 675

Advanced Glycosylation End Product Specific Receptor (AGER) Antibody

abx104577-20g 20 µg
EUR 250

Advanced Glycosylation End Product Specific Receptor (AGER) Antibody

abx104577-50g 50 µg
EUR 312.5

Advanced Glycosylation End Product Specific Receptor (AGER) Antibody

abx104578-100g 100 µg
EUR 687.5

Advanced Glycosylation End Product Specific Receptor (AGER) Antibody

abx104578-20g 20 µg
EUR 262.5

Advanced Glycosylation End Product Specific Receptor (AGER) Antibody

abx104578-50g 50 µg
EUR 325

Human AGER (Advanced Glycosylation End Product Specific Receptor) ELISA Kit

EKE60221-5x96T 5x96T
EUR 3124.08

Human AGER (Advanced Glycosylation End Product Specific Receptor) ELISA Kit

EKE60221-96T 96T
EUR 657.7

Human AGER(Advanced Glycosylation End Product Specific Receptor) ELISA Kit

ELK1852-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human AGER. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human AGER. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human AGER, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human AGER in the samples is then determined by comparing the OD of the samples to the standard curve.

Human AGER(Advanced Glycosylation End Product Specific Receptor) ELISA Kit

ELK1852-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human AGER. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human AGER. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human AGER, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human AGER in the samples is then determined by comparing the OD of the samples to the standard curve.

Human AGER (Advanced Glycosylation End Product Specific Receptor) ELISA Kit

MBS8800853-10x96StripWells 10x96-Strip-Wells
EUR 3130

Human AGER (Advanced Glycosylation End Product Specific Receptor) ELISA Kit

MBS8800853-48StripWells 48-Strip-Wells
EUR 350

Human AGER (Advanced Glycosylation End Product Specific Receptor) ELISA Kit

MBS8800853-5x96StripWells 5x96-Strip-Wells
EUR 1710

Human AGER (Advanced Glycosylation End Product Specific Receptor) ELISA Kit

MBS8800853-96StripWells 96-Strip-Wells
EUR 445

Human Total Advanced Glycosylation End Product Specific Receptor CLIA Kit

MBS8425082-INQUIRE INQUIRE Ask for price

Human AGER (Advanced Glycosylation End Product Specific Receptor) ELISA Kit

MBS2514152-10x96Tests 10x96Tests
EUR 4060

Human AGER (Advanced Glycosylation End Product Specific Receptor) ELISA Kit

MBS2514152-24Tests 24Tests
EUR 265

Human AGER (Advanced Glycosylation End Product Specific Receptor) ELISA Kit

MBS2514152-48Tests 48Tests
EUR 450

Human AGER (Advanced Glycosylation End Product Specific Receptor) ELISA Kit

MBS2514152-5x96Tests 5x96Tests
EUR 2265

Human AGER (Advanced Glycosylation End Product Specific Receptor) ELISA Kit

MBS2514152-96Tests 96Tests
EUR 535

Rat Advanced Glycosylation End Product Specific Receptor ELISA kit

E02A0477-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rat Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Advanced Glycosylation End Product Specific Receptor ELISA kit

E02A0477-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rat Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rat Advanced Glycosylation End Product Specific Receptor ELISA kit

E02A0477-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rat Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Advanced Glycosylation End Product Specific Receptor ELISA kit

E06A0477-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Goat Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Advanced Glycosylation End Product Specific Receptor ELISA kit

E06A0477-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Goat Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Goat Advanced Glycosylation End Product Specific Receptor ELISA kit

E06A0477-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Goat Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Advanced Glycosylation End Product Specific Receptor ELISA kit

E08A0477-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Canine Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Advanced Glycosylation End Product Specific Receptor ELISA kit

E08A0477-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Canine Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Dog Advanced Glycosylation End Product Specific Receptor ELISA kit

E08A0477-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Canine Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Advanced Glycosylation End Product Specific Receptor ELISA kit

E07A0477-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Porcine Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Advanced Glycosylation End Product Specific Receptor ELISA kit

E07A0477-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Porcine Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Pig Advanced Glycosylation End Product Specific Receptor ELISA kit

E07A0477-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Porcine Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Cat Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS099645-INQUIRE INQUIRE Ask for price

Fish Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS007269-INQUIRE INQUIRE Ask for price

Cavy Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS007520-INQUIRE INQUIRE Ask for price

Rat Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS023247-10x96StripWells 10x96-Strip-Wells
EUR 6725

Rat Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS023247-48StripWells 48-Strip-Wells
EUR 550

Rat Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS023247-5x96StripWells 5x96-Strip-Wells
EUR 3420

Rat Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS023247-96StripWells 96-Strip-Wells
EUR 765

Goat Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS017050-INQUIRE INQUIRE Ask for price

Duck Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS086801-INQUIRE INQUIRE Ask for price

Human Advanced Glycosylation End Product Specific Receptor / RAGE (AGER) CLIA Kit

20-abx491820
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

ELISA kit for Human AGER (Advanced Glycosylation End Product Specific Receptor)

ELK1852 1 plate of 96 wells
EUR 518.4
Description: A sandwich ELISA kit for detection of Advanced Glycosylation End Product Specific Receptor from Human in samples from blood, serum, plasma, cell culture fluid and other biological fluids.

Rat Advanced Glycosylation End Product Specific Receptor (AGER) Protein

20-abx168527
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  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug

Rat Advanced Glycosylation End Product Specific Receptor (AGER) Protein

abx168527-1ml 1 ml
EUR 225

Mouse Advanced Glycosylation End Product Specific Receptor ELISA kit

E03A0477-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Mouse Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Advanced Glycosylation End Product Specific Receptor ELISA kit

E03A0477-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Mouse Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Mouse Advanced Glycosylation End Product Specific Receptor ELISA kit

E03A0477-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Mouse Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Advanced Glycosylation End Product Specific Receptor ELISA kit

E04A0477-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Rabbit Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Advanced Glycosylation End Product Specific Receptor ELISA kit

E04A0477-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Rabbit Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Rabbit Advanced Glycosylation End Product Specific Receptor ELISA kit

E04A0477-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Rabbit Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Advanced Glycosylation End Product Specific Receptor ELISA kit

E09A0477-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Monkey Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Advanced Glycosylation End Product Specific Receptor ELISA kit

E09A0477-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Monkey Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Monkey Advanced Glycosylation End Product Specific Receptor ELISA kit

E09A0477-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Monkey Advanced Glycosylation End Product Specific Receptor in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Donkey Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS095962-INQUIRE INQUIRE Ask for price

Pigeon Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS097304-INQUIRE INQUIRE Ask for price

Camel Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS097708-10x96StripWells 10x96-Strip-Wells
EUR 6725

Camel Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS097708-48StripWells 48-Strip-Wells
EUR 550

Camel Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS097708-5x96StripWells 5x96-Strip-Wells
EUR 3420

Camel Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS097708-96StripWells 96-Strip-Wells
EUR 765

Goose Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS008609-INQUIRE INQUIRE Ask for price

Canine Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS010081-10x96StripWells 10x96-Strip-Wells
EUR 6725

Canine Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS010081-48StripWells 48-Strip-Wells
EUR 550

Canine Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS010081-5x96StripWells 5x96-Strip-Wells
EUR 3420

Canine Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS010081-96StripWells 96-Strip-Wells
EUR 765

Horse Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS015844-10x96StripWells 10x96-Strip-Wells
EUR 6725

Horse Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS015844-48StripWells 48-Strip-Wells
EUR 550

Horse Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS015844-5x96StripWells 5x96-Strip-Wells
EUR 3420

Horse Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS015844-96StripWells 96-Strip-Wells
EUR 765

Monkey Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS031620-10x96StripWells 10x96-Strip-Wells
EUR 6725

Monkey Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS031620-48StripWells 48-Strip-Wells
EUR 550

Monkey Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS031620-5x96StripWells 5x96-Strip-Wells
EUR 3420

Monkey Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS031620-96StripWells 96-Strip-Wells
EUR 765

Sheep Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS040095-10x96StripWells 10x96-Strip-Wells
EUR 6725

Sheep Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS040095-48StripWells 48-Strip-Wells
EUR 550

Sheep Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS040095-5x96StripWells 5x96-Strip-Wells
EUR 3420

Sheep Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS040095-96StripWells 96-Strip-Wells
EUR 765

Bovine Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS041914-10x96StripWells 10x96-Strip-Wells
EUR 6725

Bovine Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS041914-48StripWells 48-Strip-Wells
EUR 550

Bovine Advanced Glycosylation End Product Specific Receptor ELISA Kit

MBS041914-5x96StripWells 5x96-Strip-Wells
EUR 3420

Based on cytokine measurements in this study, the sample size required to detect a statistically significant increase in cytokine with 90% power and 5% significance is determined to be n = 9 for CD28SA and n = 5 for alemtuzumab. The most sensitive marker is IL-8. The results showed that the WBCA is the design of a practical test that can warn of potential risks alemtuzumab FcγR-mediated and T-cell activating CD28SA but, as there appears to lower response to CD28SA, it can not be used as a risk-rating.